U.S. Route 277 is a north–south United States Highway that is a spur route of U.S. Route 77. It no longer connects to its parent route, US 77, although it does intersect another one of its spur. It runs for 633 miles (1,019 km) across Oklahoma and Texas. US 277's northern terminus is in Newcastle, Oklahoma at Interstate 44, which is also the northern terminus of the H.E. Bailey Turnpike. Its southern terminus is in Carrizo Springs, Texas at U.S. Route 83. It passes through the states of Oklahoma and Texas.

Chickasha is a city in and the county seat of Grady County, Oklahoma, United States. The population was 16,051 at the 2020 census, a 0.1% increase from 2010. The city is named for and strongly connected to Native American heritage, as "Chickasha" (Chikashsha) is the Choctaw word for Chickasaw. Chickasha is home to the University of Science and Arts of Oklahoma.