U.S. Route 45 is a major north-south United States highway and a border-to-border route, from Lake Superior to the Gulf of Mexico. A sign at the highway's northern terminus notes the total distance as 1,297 miles (2,087 km).
Failure of the Mississippi Highway 25 N/U.S. Route 45 S bridge over the Tombigbee River relief (Big Nichols Creek)/Tennessee–Tombigbee Waterway in Aberdeen, Mississippi, during the March 1955 floods.
US 45 Bypass signage in Jackson, Tennessee
U.S. Route 45 crosses the Ohio River between Kentucky and Illinois on the Brookport Bridge.
The highway near Oshkosh, Wisconsin
Meridian is the eighth most populous city in the U.S. state of Mississippi, with a population of 35,052 at the 2020 census. It is the county seat of Lauderdale County and the principal city of the Meridian, Mississippi Micropolitan Statistical Area. Along major highways, the city is 93 mi (150 km) east of Jackson; 154 mi (248 km) southwest of Birmingham, Alabama; 202 mi (325 km) northeast of New Orleans, Louisiana; and 231 mi (372 km) southeast of Memphis, Tennessee.
Image: Downtown Meridian from City Hall
Image: Meridian December 2018 19 (Meridian City Hall)
Image: Meridian December 2018 20 (Meridian Museum of Art)
Image: Riley Center Meridian MS