U.S. Route 45 in the state of Illinois is a major north–south U.S. Highway that runs from the Brookport Bridge over the Ohio River at Brookport north through rural sections of eastern Illinois and the

Illinois Route 22, also known as Half Day Road for part of its length, is an east–west state highway in northeastern Illinois. It runs from U.S. Route 14 in Fox River Grove to U.S. Route 41 in Highlan