U.S. Route 521 is a north–south United States Highway that traverses 177.3 miles, from Georgetown, South Carolina, to Charlotte, North Carolina. Though numbered as an auxiliary route of US 21, it does
U.S. Route 301 is a 189.704-mile U.S. Highway that travels north–south from the Savannah River southwest of Allendale to Hamer approaching the South of the Border roadside attraction complex.
U.S. Route 521
…Highway. There is a brief section right before Manning where it runs concurrent with SC 261. In Manning SC 261 branches off and US 521 merges with US 301 for a short distance. It crosses over Interstate 95 (I-95) and heads to the city of Sumter. In Sumter, it runs together with US Business 378. Leaving…