U.S. Route 63 is the portion of a north-south highway that runs through the U.S. state of Missouri from the Arkansas state line near Thayer to the Iowa state line near Lancaster.

Rolla is a city in, and the county seat of, Phelps County, Missouri, United States. Its population in the 2020 United States Census was 19,943. It is approximately midway between St. Louis and Springfield along I-44. Its micropolitan statistical area consists of Phelps County, Missouri.