U.S. Route 77 (US 77) is a major highway that is part of the United States Numbered Highway System that runs from the Veterans International Bridge in Brownsville to Sioux City, Iowa. In Texas, the road runs south-north for 471.3 miles (758.5 km) from the International border with Mexico to the Oklahoma state line north of Gainesville. The highway is being upgraded to a freeway near Corpus Christi to connect to the freeway part of the highway in Raymondville as part of future I-69. A freeway in Robstown is already signed as part of I-69. From Waco to the Oklahoma state line, US 77 overlaps or runs parallel to I-35/I-35E.

Corpus Christi is a coastal city in the South Texas region of the U.S. state of Texas and the county seat and largest city of Nueces County with portions extending into Aransas, Kleberg, and San Patricio counties. It is 130 miles (210 km) southeast of San Antonio and 208 miles (335 km) southwest of Houston. Its political boundaries encompass Nueces Bay and Corpus Christi Bay. Its zoned boundaries include small land parcels or water inlets of three neighboring counties.