U.S. Route 79 is a U.S. highway that begins in the state of Texas at Interstate 35 in Round Rock. The highway travels northeast–southwest through the state, crossing into Louisiana approximately 23 miles northeast of Carthage. US 79 is entwined with two tragedies of country music: Johnny Horton was killed by a drunk driver on the highway near Milano in 1960 and Jim Reeves, killed in a plane crash in 1964, is buried and memorialized on US 79 in his hometown of Carthage.

Interstate 35 (I-35) is a major north–south Interstate Highway that runs from Laredo, Texas near the Mexican border to Duluth, Minnesota. In Texas, the highway begins in Laredo and runs north to the Red River north of Gainesville, where it crosses into Oklahoma. Along its route, it passes through the cities of San Antonio, Austin, and Waco before splitting into two branch routes just north of Hillsboro: I-35E heads northeast through Dallas, while I-35W turns northwest to run through Fort Worth. The two branches rejoin in Denton to again form I-35, which continues to the Oklahoma state line. The exit numbers for I-35E maintain the sequence of exit numbers from the southern segment of I-35, and the northern segment of I-35 follows on from the sequence of exit numbers from I-35E. I-35W maintains its own sequence of exit numbers.