U.S. Route 90 is a major east–west highway in the U.S. state of Texas with large portions of it running concurrently with I-10. US 90 begins at Bus. I-10 in Van Horn, travels through San Antonio and Houston, and continues on into the state of Louisiana.

Interstate business routes are roads connecting a central or commercial district of a city or town with an Interstate bypass. These roads typically follow along local streets often along a former US route or state highway that had been replaced by an Interstate. Interstate business route reassurance markers are signed as either loops or spurs using a green shield shaped and numbered like the shield of the parent Interstate highway.