UFC on ESPN: Holm vs. Aldana was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on October 4, 2020 at the du Forum on Yas Island, Abu Dhabi, United Arab Emirates.

Holly Holm is an American mixed martial artist. She competes in the Ultimate Fighting Championship, where she is a former Women's Bantamweight Champion. Also a former professional boxer, Holm was a multiple-time world champion, defending her titles 18 times in three weight classes, and a two-time Ring magazine fighter of the year. She is ranked by BoxRec as the 12th greatest female professional boxer of all time, pound for pound.