USCGC Hamilton (WMSL-753) is the fourth Legend-class cutter, also known as the National Security Cutter (NSC), of the United States Coast Guard. She is the fifth cutter named after Founding Father Alexander Hamilton, who was the first United States Secretary of the Treasury and in that position requested the formation of the United States Coast Guard. The cutter's sponsor is Linda Kapral Papp, the wife of Coast Guard Commandant Robert J. Papp Jr.

The Legend-class cutter, also known as the National Security Cutter (NSC) and Maritime Security Cutter, Large, is the largest active patrol cutter class of the United States Coast Guard, with the size of a frigate. Entering into service in 2008, the Legend class is the largest of several new cutter designs developed as part of the Integrated Deepwater System Program.