The USC Trojans baseball program represents the University of Southern California in college baseball. Established in 1888, the team is a member of the National Collegiate Athletic Association and the Pac-12 Conference. USC’s home field is Dedeaux Field, which is named in honor of former head coach and National College Baseball Hall of Fame inductee Rod Dedeaux.

College baseball is baseball that is played on the intercollegiate level at institutions of higher education. In the United States, college baseball is sanctioned mainly by the National Collegiate Athletic Association (NCAA); in Japan, it is governed by the All Japan University Baseball Federation (JUBF).