USS Andrew Jackson (SSBN-619) was a Lafayette-class nuclear-powered ballistic missile submarine. It was the second ship of the United States Navy to be named for Andrew Jackson (1767–1845), the seventh President of the United States (1829–1837).

The Lafayette class of submarine was an evolutionary development from the Ethan Allen class of fleet ballistic missile submarine, slightly larger and generally improved. This class, together with the George Washington, Ethan Allen, James Madison, and Benjamin Franklin classes, composed the "41 for Freedom," the Navy's primary contribution to the nuclear deterrent force through the late 1980s. The James Madison and Benjamin Franklin classes are combined with the Lafayettes in some references.