USS Buffalo (SSN-715) was a Los Angeles-class submarine, the second vessel that actively served the United States Navy to be named for Buffalo, New York. The contract to build her was awarded to Newport News Shipbuilding and Dry Dock Company in Newport News, Virginia on 23 February 1976, and her keel was laid down on 25 January 1980. She was launched on 8 May 1982 sponsored by Mrs. Joanne Kemp, wife of former Buffalo Bills quarterback and New York's 31st congressional district representative Jack Kemp, who was credited with winning approval to name the ship after the city in his district. Buffalo was commissioned on 5 November 1983, with Commander G. Michael Hewitt in command. Buffalo was decommissioned on 30 January 2019 after 35 years of service.

The Los Angeles class of submarines are nuclear-powered fast attack submarines (SSN) in service with the United States Navy. Also known as the 688 class after the hull number of lead vessel USS Los Angeles (SSN-688), 62 were built from 1972 to 1996, the latter 23 to an improved 688i standard. As of 2024, 24 of the Los Angeles class remain in commission—more than any other class in the world—and they account for almost half of the U.S. Navy's 50 fast attack submarines.