USS Curtis Wilbur is the fourth Arleigh Burke-class guided missile destroyer. Curtis Wilbur was named for Curtis D. Wilbur, forty-third Secretary of the Navy, who served under President Calvin Coolidge. In 2016, she was based at Yokosuka, Japan, as part of Destroyer Squadron 15.

A guided-missile destroyer (DDG) is a destroyer whose primary armament is guided missiles so they can provide anti-aircraft warfare screening for the fleet. The NATO standard designation for these vessels is DDG, while destroyers which have a primary gun armament or a small number of anti-aircraft missiles sufficient only for point-defense are designated DD. Nations vary in their use of destroyer D designation in their hull pennant numbering, either prefixing or dropping it altogether.