USS Gwin (DD-71) was one of six Caldwell-class destroyers built for the United States Navy. She was in commission from 1920 to 1922.

The Caldwell class was a class of six "flush deck" United States Navy destroyers built during World War I and shortly after. Four served as convoy escorts in the Atlantic; the other two were completed too late for wartime service. Two were scrapped during the 1930s, but four survived to serve throughout World War II, three of these in service with the Royal Navy under the Destroyers for Bases Agreement and the fourth as a high speed transport.