USS Houston (CL-81) was a Cleveland-class light cruiser of the United States Navy, which were built during World War II. The class was designed as a development of the earlier Brooklyn-class cruisers, the size of which had been limited by the First London Naval Treaty. The start of the war led to the dissolution of the treaty system, but the dramatic need for new vessels precluded a new design, so the Clevelands used the same hull as their predecessors, but were significantly heavier. The Clevelands carried a main battery of twelve 6-inch (152 mm) guns in four three-gun turrets, along with a secondary armament of twelve 5 in (127 mm) dual-purpose guns. They had a top speed of 32.5 knots.

The Cleveland class was a group of light cruisers built for the U.S. Navy during World War II. They were the most numerous class of light cruisers ever built. Fifty-two were ordered, and 36 were completed, 27 as cruisers and nine as light aircraft carriers. They were deactivated within a few years after the end of the war, but six were converted into missile ships, and some of these served into the 1970s. One ship of the class remains as a museum ship.