USS Russell (DDG-59) is an Arleigh Burke-class destroyer in the United States Navy. She is the second ship of the USN to carry the name Russell and is named for Rear Admiral John Henry Russell and his son, Commandant of the Marine Corps John Henry Russell, Jr.

The Arleigh Burke class of guided-missile destroyers (DDGs) is a United States Navy class of destroyer centered around the Aegis Combat System and the SPY-1D multi-function passive electronically scanned array radar. The class is named for Admiral Arleigh Burke, an American destroyer officer in World War II and later Chief of Naval Operations. With an overall length of 505 to 509.5 feet, displacement ranging from 8,300 to 9,700 tons, and weaponry including over 90 missiles, the Arleigh Burke-class destroyers are larger and more heavily armed than many previous classes of guided-missile cruisers.