The UTSA Roadrunners football program represents the University of Texas at San Antonio (UTSA) in the sport of American football. The Roadrunners compete in the Football Bowl Subdivision (FBS) of the National Collegiate Athletic Association (NCAA) and the American Athletic Conference. They are coached by Jeff Traylor, who started in 2020. The Roadrunners play their home games at the Alamodome, which has a seating capacity of 65,000 but whose capacity for UTSA games is normally restricted to 36,582.

The University of Texas at San Antonio (UTSA) is a public research university in San Antonio, Texas. With over 34,000 students across its four campuses spanning more than 758 acres, UTSA is the largest university in San Antonio and the eighth-largest by enrollment in the state of Texas. It is classified among "R1: Doctoral Universities – Very High Research Activity" and offers over 170 degree options from its nine colleges.