The Uncompahgre River is a tributary of the Gunnison River, approximately 75 mi (121 km) long, in southwestern Colorado in the United States. Lake Como at 12,215 ft (3723m) in northern San Juan County, in the Uncompahgre National Forest in the northwestern San Juan Mountains is the headwaters of the river. It flows northwest past Ouray, Ridgway, Montrose, and Olathe and joins the Gunnison at Confluence Park in Delta.

Delta is a home rule municipality that is the county seat and the most populous municipality of Delta County, Colorado, United States. The town population was 9,035 at the 2020 United States Census. The United States Forest Service headquarters of the Grand Mesa, Gunnison, and Uncompahgre National Forests are located in Delta.