Wilmington Union Station was a union station in Wilmington, North Carolina. Opened in 1913, it was designed by architect Joseph F. Leitner. Construction by Boyle-Robertson contractors began in 1912. It was located at Front Street and Red Cross Street in downtown Wilmington.

Joseph Florence Leitner was an American architect whose work includes several rail stations. In Columbia, South Carolina he worked for Charles Coker Wilson for five years. Later he partnered with William J. Wilkins (architect), first in Florence, South Carolina and then in an office in Wilmington, North Carolina, where Leitner practiced for a decade. to form Leitner & Wilkins. His work included commercial, educational, fraternal religious, industrial, residential, and transportation buildings in colonial revival architecture, Flemish architecture (especially gables, Italianate architecture and Romanesque revival architecture styles. He ended his career in Florida.