The United Nations Development Fund for Women was established in December 1976 originally as the Voluntary Fund for the United Nations Decade for Women in the International Women's Year. Its first director was Margaret C. Snyder. UNIFEM provided financial and technical assistance to innovative programmes and strategies that promoted women's human rights, political participation and economic security. Since 1976 it supported women's empowerment and gender equality through its programme offices and links with women's organizations in the major regions of the world. Its work on gender responsive budgets began in 1996 in Southern Africa and expanded to include East Africa, Southeast Asia, South Asia, Central America and the Andean region. It worked to increase awareness throughout the UN system of gender responsive budgets as a tool to strengthen economic governance in all countries. In 2011, UNIFEM merged with some other smaller entities to become UN Women.

The United Nations System consists of the United Nations' six principal bodies, the Specialized Agencies and related organizations. The UN System includes subsidiary bodies such as the separately administered funds and programmes, research and training institutes, and other subsidiary entities. Some of these organizations predate the founding of the United Nations in 1945 and were inherited after the dissolution of the League of Nations.