The United States Army Space and Missile Defense Command (USASMDC) is the Army Service Component Command (ASCC) for United States Strategic Command and United States Space Command. It was established in 1985 as the Army Strategic Defense Command, responsible for ballistic missile defense. In 1992, it merged with Army Space Command to become Army Space and Strategic Defense Command. In 1997, it became an Army Major Command and was redesignated Army Space and Missile Defense Command.

The United States Space Command is a unified combatant command of the United States Department of Defense, responsible for military operations in outer space, specifically all operations 100 kilometers and greater above mean sea level. U.S. Space Command is responsible for the operational employment of space forces that are provided by the uniformed services of the Department of Defense.