The United States National Professional Road Race Championships began in 1985. They are run by the governing body, USA Cycling. Until 2006 the race was open to all nationalities, the first American to finish being named the winner and given a distinctive jersey. Since the championship in Greenville, South Carolina, in 2006, all riders have had to be American.

Levi Leipheimer is an American former professional road racing cyclist. He was twice US national champion, winning the time trial title in 1999 and the road race in 2007, and is an Olympic medalist. Leipheimer was born and raised in Butte, Montana and resides in Santa Rosa, California. He is the patron of the widely attended King Ridge GranFondo, a mass participation ride in Sonoma County.