The United States Public Health Service Commissioned Corps is the uniformed service branch of the United States Public Health Service and one of the eight uniformed services of the United States. The commissioned corps' primary mission is the protection, promotion, and advancement of health and safety of the general public.

The United States Public Health Service is a collection of agencies of the Department of Health and Human Services concerned with public health, containing nine out of the department's twelve operating divisions. The Assistant Secretary for Health oversees the PHS. The Public Health Service Commissioned Corps (PHSCC) is the federal uniformed service of the PHS, and is one of the eight uniformed services of the United States.