The School of Music is an academic division of the University of Missouri in Columbia, Missouri. Its focus is the study of music, awarding baccalaureate, master's, and doctoral degrees as part of the College of Arts and Science. The institution's programs encompass composition, performance, conducting, music education, music history, musical theatre and musicology. Established in 1917 as the Department of Music, the school continues to play a prominent role in the cultural life of Missouri and is located in the Sinquefield Music Center, on the university's flagship campus in Downtown Columbia. The Fine Arts Building also houses classrooms, studios, and a recital hall. Its major performance venues are Jesse Hall, the Missouri Theatre, and Whitmore Recital Hall. The Missouri Tigers marching band, Marching Mizzou, performs at Faurot Field for Southeastern Conference football games. The school's ensembles have performed worldwide and can be heard weekly on the university's own KMUC 90.5 FM Classical, Mid-Missouri's classical music radio station. Alumni include singers Sheryl Crow and Neal Boyd, Canadian Brass founder Gene Watts, and jazz artist Mike Metheny.

The University of Missouri is a public land-grant research university in Columbia, Missouri. It is Missouri's largest university and the flagship of the four-campus University of Missouri System. MU was founded in 1839 as the first public university west of the Mississippi River. It has been a member of the Association of American Universities since 1908 and is classified among "R1: Doctoral Universities – Very high research activity".