Upper Myanmar is one of two geographic regions in Myanmar, the other being Lower Myanmar. Located in the country's centre and north stretches, Upper Myanmar encompasses 6 inland states and regions, including Mandalay, Sagaing, Magway Regions, and Chin, Kachin and Shan States. By contrast, Lower Myanmar encompasses the southern and coastal-facing regions of Myanmar. Upper Myanmar is home to several distinct cultural regions, including the homeland of the Bamar in the low-lying central plains, and those of the Chin, Kachin, and Shan peoples in the highlands. Home to over 23 million people, the region's agricultural sector, natural resources, and shared borders with India, China, and Thailand have made Upper Myanmar a major economic hub. Four of Myanmar's ten largest cities, Mandalay, Taunggyi, Monywa, and Myitkyina, are located in the region.

Burmese is a Sino-Tibetan language spoken in Myanmar, where it is the official language, lingua franca, and the native language of the Bamar, the country's principal ethnic group. Burmese is also spoken by the indigenous tribes in Chittagong Hill Tracts in Bangladesh, and in Tripura state in India. The Constitution of Myanmar officially refers to it as the Myanmar language in English, though most English speakers continue to refer to the language as Burmese, after Burma—a name with co-official status that had historically been predominantly used for the country. Burmese is the most widely-spoken language in the country, where it serves as the lingua franca. In 2007, it was spoken as a first language by 33 million. Burmese is spoken as a second language by another 10 million people, including ethnic minorities in Myanmar like the Mon and also by those in neighboring countries. In 2022, the Burmese-speaking population was 38.8 million.