The Upper Ruhr Valley Railway is a 138-kilometre-long, non-electrified line from Schwerte (Ruhr) station) through the Hochsauerland to Warburg in the German state of North Rhine-Westphalia. It is the most southerly of the east-west lines that run from the Ruhr to eastern Germany and it connects the rural Hochsauerlandkreis with the Ruhr. The line is included in the German railway timetable as line 435, which continues on the line from Schwerte to Hagen, which is part of the Hagen–Hamm railway.

The Warburg station is located on the north-eastern edge of the German town of Warburg.