Urbino is a comune (municipality) in the Italian region of Marche, southwest of Pesaro, a World Heritage Site notable for a remarkable historical legacy of independent Renaissance culture, especially under the patronage of Federico da Montefeltro, duke of Urbino from 1444 to 1482.

Marche, in English sometimes referred to as the Marches, is one of the twenty regions of Italy. The region is located in the central area of the country, and has a population of about 1.5 million people, being the thirteenth largest region in the country by number of inhabitants. The region's capital and largest city is Ancona.