Vanderburgh County is a county in the U.S. state of Indiana. As of 2020, the population was 180,136. The county seat is in Evansville. While Vanderburgh County was the eighth-largest county in 2020 population in Indiana, it is also the eighth-smallest county in area and the smallest in southwestern Indiana, covering only 236 square miles (610 km2).

Evansville is a city in and the county seat of Vanderburgh County, Indiana, United States. With a population of 118,414 at the 2020 census, it is Indiana's third-most populous city after Indianapolis and Fort Wayne, the most populous city in Southern Indiana, and the 249th-most populous city in the United States. It is the central city of the Evansville metropolitan area, a hub of commercial, medical, and cultural activity of southwestern Indiana and the Illinois–Indiana–Kentucky tri-state area, which is home to over 911,000 people. The 38th parallel north crosses the north side of the city and is marked on Interstate 69 immediately north of its junction with Indiana 62 within the city's east side.