Vanessa Polster Bayer is an American actress, comedian and writer. She was a cast member on the NBC sketch comedy series Saturday Night Live from 2010 to 2017, for which she was nominated for an Emmy. She co-created, co-executive produces, and has the lead role in the Showtime comedy I Love That for You, loosely based on her experience as a survivor of childhood leukemia. She has appeared in such films as Trainwreck (2015), Office Christmas Party (2016), Carrie Pilby (2016), Ibiza (2018) and Wander Darkly (2020).

Trainwreck is a 2015 American romantic sex comedy film directed and co-produced by Judd Apatow and written by and starring Amy Schumer along with an ensemble supporting cast that includes Bill Hader, Brie Larson, Colin Quinn, John Cena, Vanessa Bayer, Tilda Swinton, Ezra Miller, Mike Birbiglia, Norman Lloyd, and NBA legend LeBron James. The film is about a hard-drinking, promiscuous, free-spirited young magazine writer named Amy Townsend (Schumer) who has her first serious relationship with a prominent orthopedic surgeon named Aaron Conners (Hader). The film received positive reviews from critics, praising the performances of Schumer, Hader, James, and the screenplay.