The Vendsyssel railway line is a 80.7 km (50.1 mi) long standard gauge single track railway line in Denmark which runs through the historical region of Vendsyssel between Aalborg and Frederikshavn in North Jutland. It constitutes the northernmost part of the East Jutland longitudinal railway line, the through route along the east coast of the Jutland Peninsula from the German border at Padborg to Frederikshavn.

Frederikshavn is a Danish town in Frederikshavn municipality, Region Nordjylland, on the northeast coast of the Jutland peninsula in northern Denmark. Its name translates to "Frederik's harbor". It was originally named Fladstrand.