The 2015 Pan and Parapan American Games venues were mostly located in the host city of Toronto, Ontario, though some events required facilities located elsewhere. Besides Toronto, fourteen other municipalities in Southern Ontario hosted competitions: Ajax, Hamilton, Innisfil, Markham, Milton, Minden, Mississauga, Mono, Oro-Medonte, Oshawa, Palgrave, St. Catharines, Welland and Whitby.

York Lions Stadium is an outdoor sports stadium on the Keele Campus of Toronto's York University in the former city of North York. It is home to the York Lions, the varsity teams of York University, the Toronto Arrows of Major League Rugby and York United of the Canadian Premier League. The facility was primarily built for the 2015 Pan American and Parapan American Games, where it hosted track and field events and the opening ceremony. In 2021, the stadium's running track was removed to expand the playing surface used for football and soccer.