Vermont Route 100 (VT 100) is a north–south state highway in Vermont in the United States. Running through the center of the state, it travels nearly the entire length of Vermont and is 216.666 miles (349 km) long. VT 100 is the state's longest numbered highway of any type.

Ludlow is a town in Windsor County, Vermont, United States. The population was 2,172 at the 2020 census. Ludlow is the home of Okemo Mountain, a popular ski resort. Before becoming a ski destination, Ludlow was originally a mill town, and was the home of a General Electric plant until 1977. It was arguably the most impacted by the flooding and natural disaster which ravaged Vermont in July 2023. The town of Ludlow was named after Ludlow, Massachusetts which is less than 100 miles away. There is also, where the town started, a village of Ludlow located in the town.