The vice presidents of Honduras, officially the Designates to the Presidency, is the second highest political position in Honduras. According to the current constitution, the president and vice-presidents are elected in the same ticket. From 1957 to 2006 and from 2010 onwards there are positions of first, second, and third vice-president commonly known as the presidential designates.

The president of Honduras, officially known as the President of the Republic of Honduras, is the head of state and head of government of Honduras, and the Commander-in-chief of the Armed Forces. According to the 1982 Constitution of Honduras, the Government of Honduras consists of three branches: Executive, Legislative and Judicial. The president is the head of the Executive branch, their primary duty being to "execute and enforce the Constitution, treaties and conventions, laws and other legal dispositions". The President is directly elected for a four-year term.