The vice president of Uruguay is the person with the second highest position in the executive branch of the Uruguayan government, after the President of Uruguay. The Vice President replaces the elected President in case of his death or absence. The vice president is also an officer in the legislative branch, as president of the Chamber of Senators and of the General Assembly.

The president of Uruguay, officially known as the president of the Oriental Republic of Uruguay, is the head of state and head of government of Uruguay. Their rights are determined in the Constitution of Uruguay. Along with the Secretariat of the Presidency, the Council of Ministers and the director of the Office of Planning and Budget, the President is part of the executive branch. In case of absence, their office is exercised by the vice president. In turn, the president of the republic is the commander in chief of the Armed Forces.