Victoria Barracks Melbourne is an Australian Government building located on St Kilda Road in Melbourne, Australia. It was constructed in the mid-to-late 19th century as barracks for British colonial forces in Australia and was the headquarters of the Department of Defence from 1901 to 1953, also housing Australia's war cabinet during World War II. It is still used as a Department of Defence administrative centre in the present day.

St Kilda Road is a street in Melbourne, Victoria, Australia. It is part of the locality of Melbourne which has the postcode of 3004, and along with Swanston Street forms a major spine of the city.