Villa Clara is one of the provinces of Cuba. It is located in the central region of the island bordering on the Atlantic Ocean to the north, Matanzas Province to the west, Sancti Spiritus Province to the east, and Cienfuegos Province to the South. Villa Clara shares with Cienfuegos and Sancti Spiritus on the south the Escambray Mountain Range. Its main cities are Santa Clara, Remedios, Sagua La Grande, Camajuani, Caibarién, Ranchuelo, Placetas, and Manicaragua.

Sancti Spíritus is one of the provinces of Cuba. Its capital is the identically named Sancti Spíritus. Another major city is Trinidad.