Villa Guardamangia, formerly known as Casa Medina and sometimes referred to as Casa Guardamangia, is a 16,791 square feet (1,559.9 m2) townhouse in Gwardamanġa, Pietà, Malta, which served as the residence of Princess Elizabeth, Duchess of Edinburgh, and Prince Philip, Duke of Edinburgh, between 1949 and 1951, while Philip was stationed in Malta as a naval officer.

Gwardamanġa is a hamlet in Pietà, Malta. Gwardamanġa is the home of St. Luke's Hospital, Malta's former general public hospital, and Villa Guardamangia, the former home of Queen Elizabeth II. It is also the location where the Rediffusion House is found.