The Villa of the Quintilii is a monumental ancient Roman villa beyond the fifth milestone along the Via Appia Antica just outside the traditional boundaries of Rome, Italy. It was built by the rich and cultured Quintilii brothers Sextus Quintilius Valerius Maximus and Sextus Quintilius Condianus.

A Roman villa was typically a farmhouse or country house in the territory of the Roman Republic and the Roman Empire, sometimes reaching extravagant proportions.