State Route 122 is a primary state highway in the U.S. state of Virginia. The state highway runs 54.58 miles (87.84 km) from SR 40 in Rocky Mount north to U.S. Route 501 in Big Island. SR 122 passes through the Blue Ridge foothills of Franklin and Bedford counties, connecting Rocky Mount with the town of Bedford. The state highway provides access to Booker T. Washington National Monument and Smith Mountain Lake, and the National D-Day Memorial via its Bedford business route.

State Route 40 is a primary state highway in the southern part of the U.S. state of Virginia. It runs from SR 8 at Woolwine east to SR 10 at Spring Grove, about half the width of Virginia. It is the longest state-numbered route in Virginia.