State Route 63 is a primary state highway in the U.S. state of Virginia. The state highway runs 39.28 miles (63.22 km) from U.S. Route 58 Alternate in St. Paul north to SR 80 and SR 83 in Haysi.

U.S. Route 58 Alternate is an 87.40-mile-long (140.66 km) alternate route to US 58 in western Virginia. The route is a northern bypass to US 58 which stays closer to the Tennessee border and serves Gate City and Bristol.