Virtual karyotype
Videos
In genetics, virtual karyotype is the digital information reflecting a karyotype, resulting from the analysis of short sequences of DNA from specific loci all over the genome, which are isolated and e
Fig 2. Virtual karyotype of a chronic lymphocytic leukemia sample using a SNP array.
Fig 3. Virtual karyotype log2ratio plot of a chronic lymphocytic leukemia sample using a SNP array. Yellow = copy number of 2 (normal/diploid), aqua = 1 (deletion), pink = 3 (trisomy).
Fig 5. Her2 Amplification by SNP array virtual karyotype.
Fig 6. Copy neutral LOH/uniparental disomy
Cytogenetics
Videos
Cytogenetics is essentially a branch of genetics, but is also a part of cell biology/cytology, that is concerned with how the chromosomes relate to cell behaviour, particularly to their behaviour duri
Virtual karyotype
…10q), and loss of p16 (on 9p) occur almost exclusively in glioblastoma and can provide means to distinguish anaplastic astrocytoma from glioblastoma. Cytogenetics, the study of characteristic large changes in the chromosomes of cancer cells, has been increasingly recognized as an important predictor of outcome…
Philadelphia translocation t(9;22)(q34;q11.2) seen in chronic myelogenous leukemia.
Interphase cells positive for a t(9;22) rearrangement