Wabasso is an unincorporated community and census-designated place (CDP) in Indian River County, Florida, United States. The population was 609 at the 2010 census, down from 918 at the 2000 census. It is located at the intersection of U.S. 1 and SR 510.

Indian River County is a county located in the southeastern and east-central portions of the U.S. state of Florida. As of the 2020 census, the population was 159,788. Its seat is Vero Beach. It is Florida's 7th richest county and in 2000 was the 87th richest county in the U.S. by per capita income.