"Walk on the Wild Side" is a song by American rock musician Lou Reed from his second solo studio album, Transformer (1972). It was produced by David Bowie and Mick Ronson and released as a double A-side with "Perfect Day". Known as a counterculture anthem, the song received wide radio coverage and became Reed's biggest hit and signature song while touching on topics considered taboo at the time, such as transgender people, drugs, male prostitution, and oral sex.

Holly Woodlawn was a transgender American actress and Warhol superstar who appeared in the films Trash (1970) and Women in Revolt (1971). She is also known as the Holly in Lou Reed's hit glam rock song "Walk on the Wild Side".