Warner's Ranch, near Warner Springs, California, was notable as a way station for large numbers of emigrants on the Southern Emigrant Trail from 1849 to 1861, as it was a stop on both the Gila River Trail and the Butterfield Overland Mail stagecoach line (1859-1861). It was also operated as a pioneering cattle ranch.

Southern Emigrant Trail, also known as the Gila Trail, the Kearny Trail, Southern Trail and the Butterfield Stage Trail, was a major land route for immigration into California from the eastern United States that followed the Santa Fe Trail to New Mexico during the California Gold Rush. Unlike the more northern routes, pioneer wagons could travel year round, mountain passes not being blocked by snows; however, it had the disadvantage of summer heat and lack of water in the desert regions through which it passed in New Mexico Territory and the Colorado Desert of California. Subsequently, it was a route of travel and commerce between the eastern United States and California. Many herds of cattle and sheep were driven along this route and it was followed by the San Antonio-San Diego Mail Line in 1857–1858 and then the Butterfield Overland Mail from 1858 to 1861.