State Route 397 (SR 397) is a state highway in the U.S. state of Washington, serving the Tri-Cities region. It primarily functions as a truck route through industrial areas in Finley, Kennewick, and Pasco, running 22 miles (35 km) between junctions with Interstate 82 (I-82) and I-182. The highway crosses the Columbia River on the Cable Bridge, built in 1978 to replace an earlier bridge.

The Cable Bridge, officially called the Ed Hendler Bridge and sometimes called the Intercity Bridge, spans the Columbia River between Pasco and Kennewick in southeastern Washington as State Route 397. It was constructed in 1978 and replaced the Pasco–Kennewick Bridge, an earlier span built in 1922 and demolished in 1990.