Weequahic is a neighborhood in the city of Newark in Essex County, in the U.S. state of New Jersey. Part of the South Ward, it is separated from Clinton Hill by Hawthorne Avenue on the north, and bordered by the township of Irvington on the west, Newark Liberty International Airport and Dayton on the east, and Hillside Township and the city of Elizabeth on the south. There are many well maintained homes and streets. Part of the Weequahic neighborhood has been designated a historic district; major streets are Lyons Avenue, Bergen Street, and Chancellor Avenue. Newark Beth Israel Medical Center is a major long-time institution in the neighborhood.

Newark is the most populous city in the U.S. state of New Jersey, the seat of Essex County, and a principal city of the New York metropolitan area. As of the 2020 census, the city's population was 311,549. The Population Estimates Program calculated a population of 305,344 for 2022, making it the 66th-most populous municipality in the nation.