The West Hesse Highlands, also known as the West Hessian Lowlands and Highlands, are a heavily forested region of the Central Uplands in Germany. These highlands lie mainly within the state of Hesse, between that part of the Rhenish Massif right of the Rhine in the west, the Weser Uplands to the north, the Hessian Central Uplands to the east and the Wetterau to the south.

The Central Uplands is one of the three major natural regions of Germany. It stretches east to west across the country. To the north lies the North German Plain or Northern Lowland; to the south, the Alps and the Alpine Foreland.