What's Up, Doc? is a 1972 American screwball comedy film directed by Peter Bogdanovich and starring Barbra Streisand and Ryan O'Neal. It was intended to pay homage to comedy films of the 1920s, 1930s, and 1940s, especially Bringing Up Baby and Warner Bros. Bugs Bunny cartoons. The film was loosely based on the 1971 novel A Glimpse of Tiger by Herman Raucher.

Bringing Up Baby is a 1938 American screwball comedy film directed by Howard Hawks, and starring Katharine Hepburn and Cary Grant. It was released by RKO Radio Pictures. The film tells the story of a paleontologist in a number of predicaments involving a scatterbrained heiress and a leopard named Baby. The screenplay was adapted by Dudley Nichols and Hagar Wilde from a short story by Wilde which originally appeared in Collier's Weekly magazine on April 10, 1937.