Wheeling University is a private Roman Catholic university in Wheeling, West Virginia. It was founded as Wheeling College in 1954 by the Society of Jesus and was a Jesuit institution until 2019. Wheeling University competes in Division II of the National Collegiate Athletic Association as a member of the Mountain East Conference.

Wheeling is a city in the U.S. state of West Virginia. Located almost entirely in Ohio County, of which it is the county seat, it lies along the Ohio River in the foothills of the Appalachian Mountains and also contains a tiny portion extending into Marshall County. Wheeling is located about 60 miles (96 km) west of Pittsburgh and is the principal city of the Wheeling metropolitan area. As of the 2020 census, the city had a population of 27,062, and the metro area had a population of 139,513. It is the fifth most populous city in West Virginia, and the most populous in the state’s Northern Panhandle.